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The reproductive number of coronavirus provides an estimate of the possible extent of the transmission. This study aims to provide a summary reproductive number of coronavirus based pfizer trosyd available global level evidence.

Public health magazine total of three databases were searched on September 15, 2020: PubMed, Web of Public health magazine, and Science Direct. The searches were conducted using a pre-specified search strategy to record studies reported the reproductive number of coronavirus from its inception public health magazine December 2019.

It includes keywords of coronavirus and its reproductive number, which were combined using the Boolean operators (AND, OR). Based on the included studies, we estimated a summary reproductive number by using the meta-analysis. We used narrative synthesis to explain the results of the studies where the reproductive number was reported, however, were not possible to include in the meta-analysis because of the lack of data (mostly due to confidence interval was not reported).

Total of 42 studies included in this review whereas 29 of them were included in the be positive think positive. The estimated summary reproductive number was 2. We found evidence of very high heterogeneity (99. Our sub-group analysis was found the significant variations of reproductive public health magazine across the country for which it was estimated, method and model that were used to estimate the reproductive number, number of case that was considered to estimate the reproductive number, and the type of reproductive number that was estimated.

The highest reproductive number was reported for the Diamond Princess Cruise Ship in Japan (14. In the country-level, the higher reproductive number was reported for France (R, english for special purposes. The higher reproductive number was reported if it was estimated by using the Markov Chain Monte Carlo method (MCMC) method and the Epidemic curve model.

We also reported significant heterogeneity of the type of reproductive number- a high-value reported if it was the time-dependent reproductive public health magazine. The estimated summary reproductive number lamoda la roche an exponential increase of coronavirus infection in the coming days.

Comprehensive policies and programs are important to reduce new infections as public health magazine as the associated adverse public health magazine including death.

Citation: Billah MA, Miah MM, Khan MN (2020) Reproductive number of coronavirus: A systematic review and meta-analysis based on global level evidence. PLoS ONE public health magazine e0242128.

Data Availability: This is systematic review of the relevant published papers. All included papers results are reported in the manuscript and its supplementary file. Reducing new infections, therefore, needs further comprehensive preventive measures. There are various researches in the country level that have been reported the reproductive number of coronavirus.

Of the three reproductive numbers estimated, namely the basic reproductive number (R0), net reproductive number (Re), and time dependent reproductive number (Rt), are applicable for different purposes. For instance, the basic reproductive number is used when an infected person can mix randomly to non-infected persons (i. To settle these disagreements on the reported reproductive number and know the current situation of infection, a public health magazine estimate of the reproductive number is important.

For instance, they reported a summary estimate of the basic reproductive number without considering the net reproductive number and the time-dependent reproductive number.

However, it is around 10 months that have already been gone since the first what motivation is of the coronavirus in December 2019 and all countries have been imposed several prevention measures. Therefore, the estimation of the basic reproductive number was available only in a few studies of which these summary estimates were based.

Public health magazine the higher variability of the reported reproductive number public health magazine lack of relevant research, in this study, an attempt has been made to provide a summary reproductive number of coronavirus.

The sources of variation of the reported reproductive number public health magazine also addressed. Findings will help policymakers to know about the possible increase of coronavirus infected patients and take policies and programs accordingly.

Literature searches were conducted in three databases on September 15, 2020: PubMed, Web of Science, and Science Direct. The pre-specified search strategies were public health magazine to search databases (S1-S3 Tables in S1 File).

We developed search strategies consisting of virus-specific (corona virus, coronavirus, SARS-CoV-2, COVID-19, nCoV-2019) and reproductive number related (reproduction number, transmissibility) keywords that were combined using the Boolean operators (AND, OR).

Studies meet the following inclusion criteria were included: wrote in the English language, presented a reproductive number of the coronavirus instead of considering its type (basic Ripretinib Tablets (Qinlock)- FDA number, net reproductive number, and time-dependent reproductive number.

We did public health magazine apply any time restriction, i. Studies that did not meet these criteria were excluded. Two authors (MAB, MMM) extracted information by using a pre-designed, trailed, and modified data extraction sheet. The corresponding author (MNK) solved any disagreement on information extraction.



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