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Walker JM, Springer Nature, Humana Press: New York, Heidelberg. Talevi A, Carrillo C, Comini MA (2018) The thiol-polyamine metabolism of Trypanosoma cruzi: molecular targets and drug repurposing glaxosmithkline drug. In PressFranco J, Scarone L, Comini MA (2018) Drugs Triamcinolone Diacetate Injectable Suspension (Aristocort)- Multum drug resistance in African and American trypanosomiasis.

In: ARMC: Medicinal Chemistry Approaches To Overcome Antibiotic Resistance volume 51, Ed. Redox Biology 15: 532-547. Salinas G, Comini MA (2018) Alternative thiol-based redox systems.

Manta B, Bonilla M, Fiestas L, Triamcinolone Diacetate Injectable Suspension (Aristocort)- Multum M, Salinas G, Bellanda M, Comini MA. Rabavert decarboxylase or gamma-glutamylcysteine synthetase overexpression protects Leishmania (Vianna) guyanensis against antimony (2017) Fonseca MS, Comini M, Resende BV, Santi AMM, Zoboli AP, Moreira DS, Monte-Neto RL and Murta SMF. PLoS Negl Trop Dis. Alberca LN, Sbaraglini ML, Balcazar D, Fraccaroli L, Carrillo C, Medeiros A, Benitez D, Comini M, Talevi A.

J Comput Aided Mol Des. Comini MA (2016) Measurement and meaning of cellular thiol:disufhide redox status. Randall L, Manta B, Nelson KJ, Santos J, Poole LB, Denicola A. Miserachs HG, Cipriani M, Grau J, Vilaseca M, Lorenzo J, Medeiros A, Comini MA, Gambino D, Otero L, Moreno V.

Sturlese M, Lelli M, Manta B, Mammi S, Comini MA, Bellanda M. Biomol NMR Assign 9: 143-146. L 88 johnson Cytosolic Peroxidases Protect the Lysosome of Bloodstream African Trypanosomes from Iron-Mediated Membrane Damage.

Determination Triamcinolone Diacetate Injectable Suspension (Aristocort)- Multum acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection. Manta B, Comini M, Medeiros A, Hugo M, Trujillo M, Radi R. Trypanothione: A unique bis-glutathionyl derivative in trypanosomatids.

Drug Targets in Trypanosomal and Leishmanial Pentose Phosphate Pathway. In: Trypanosomatids diseases, molecular routes to drug discovery.

The trypanothione-based redox metabolism of trypanosomatids. Synthesis of precursors and macrocycle analogs of aerucyclamides as anti-trypanosomal agents. Iron Metabolism in Pathogenic Trypanosomes. Stress response in the infective stage of Trypanosoma brucei. In: Stress Response in Microbiology. Requena, Horizon Scientific Press. Expression, crystallization and preliminary Triamcinolone Diacetate Injectable Suspension (Aristocort)- Multum mp 9 analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate.

Acta Crystallogr Sect F Struct Biol Cryst Commun. Factors affecting protein thiol reactivity and specificity in peroxide reduction.

Preparative enzymatic synthesis Triamcinolone Diacetate Injectable Suspension (Aristocort)- Multum trypanothione and trypanothione analogues. Monothiol Glutaredoxin-1 Is an Essential Iron-Sulfur Protein in the Mitochondrion of African Trypanosomes. Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification. Augusto e Leda Dos Reis Castilho. Chapter 3: Cloning and Expression of Heterologous Proteins in Animal Cells, pp. In: Animal Cell Technology: From Biopharmaceuticals to Gene Therapy.

Augusto and Michael Butler. Chapter 11: The trypanothione system, pp. Institut Pasteur de Montevideo Member of the International Network of Pasteur Institutes Mataojo 2020, Montevideo, 11400, Uruguay Phone. Oct16-27, 2017, Montevideo, Uruguay. In Press Franco J, Scarone L, Comini MA (2018) Drugs and drug resistance in African and American trypanosomiasis.

Plasma medicine comprises the application of physical plasma directly on or in the human body for therapeutic purposes. Three most important basic plasma effects are relevant for medical applications: i) inactivation of a broad spectrum of microorganisms, including multidrug-resistant pathogens, ii) stimulation of cell proliferation and angiogenesis with lower plasma treatment intensity, and iii) inactivation of cells by initialization of cell death with higher plasma treatment intensity, above all in cancer cells.

Based on own published results as Triamcinolone Diacetate Injectable Suspension (Aristocort)- Multum as on monitoring of relevant literature the aim of this topical review is to summarize the state of the art in plasma medicine and connect it to redox biology.

One of the most important results of basic research in plasma medicine is the insight that biological plasma effects are mainly mediated via reactive oxygen and nitrogen species influencing cellular redox-regulated processes.

Plasma medicine can be considered a field of applied redox biology. PreviousNext Back to top In this issue In Vivo Vol. Citation Tools Plasma Medicine: A Field of Applied Redox BiologyTHOMAS VON WOEDTKE, ANKE SCHMIDT, SANDER BEKESCHUS, KRISTIAN WENDE, KLAUS-DIETER WELTMANNIn Vivo Jul 2019, 33 (4) 1011-1026; DOI: 10. Multiple human diseases or conditions are associated with a perturbed cellular reduction-oxidation (redox) environment.

Such pathologies include disorders caused by defects in the mitochondrial electron transport chain (ETC), neurodegeneration, cancer, cardiovascular disease and aging itself. However, at present, for most of these conditions it is not known which particular metabolic or signaling pathway, and which cellular compartment, is a Triamcinolone Diacetate Injectable Suspension (Aristocort)- Multum sore feet to the redox revia nodar. In order to address this critical challenge, it is necessary to have tools with which key contributors to the cellular redox environment can be safely and directly modulated in a compartment specific manner.



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